Phosphatidylserine and ornithine‐containing lipids of Bordetella, hemagglutinins of lipoamino acid structure, and their control in biomembranes

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Abstract
From observation by light microscopy and EM, it was proved that phosphatidylserine agglutinates human erythrocytes by the same mechanism as that of ornithine-containing lipids of Bordetella described previously. The proposed mechanism was that 2 erythrocytes were bound through some liposomes of the lipoamino acids by hydrophobic and ionic interaction, and H bonding, between the lipoamino acids and the lipids or proteins in the membranes of erythrocytes. Hemagglutinating activity of phosphatidylserine might be controlled so as not to be expressed in biomembranes, because liposomes constituted of phosphatidylserine and .gtoreq. quantities of phosphatidylcholine did not exhibit hemagglutinating activity.