Postsplenectomy Infection in Cooley's Anemia

Publisher Website
Google Scholar
Abstract
IN an earlier paper1 19 cases of severe and fulminating infections, 6 terminating fatally, were reported in children after splenectomy for hematologic disorders. These observations confirmed previous experience2 3 4 that splenectomy in childhood appeared to influence susceptibility to infection. It was emphasized, however, that the incidence was small in comparison with the large number of splenectomies in children. The clinical types of infection were usually meningitis and sepsis. In a recent review Finland5 reached similar conclusions — namely, that infants and children splenectomized for serious hematologic disorders experienced a higher incidence and severity of bacterial infections than normal persons in at . . .