Overexpression of DNA polymerase β: a genomic instability enhancer process
Open Access
- 1 June 1999
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 13 (9) , 1107-1111
- https://doi.org/10.1096/fasebj.13.9.1107
Abstract
DNA polymerase β (Pol β) is the most inaccurate of the six DNA polymerases found in mammalian cells. In a normal situation, it is expressed at a constant low level and its role is believed to be rest...Keywords
This publication has 34 references indexed in Scilit:
- Mutator phenotype of BCR – ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase βOncogene, 1999
- Structural insights into DNA polymerase β fidelity: hold tight if you want it rightChemistry & Biology, 1998
- Increased Activity and Fidelity of DNA Polymerase β on Single-nucleotide Gapped DNAJournal of Biological Chemistry, 1997
- Transient Expression of a Mutator Phenotype in Cancer CellsScience, 1997
- Nucleotide Excision Repair in Mammalian CellsJournal of Biological Chemistry, 1997
- Incorporation of the Guanosine Triphosphate Analogs 8-Oxo-dGTP and 8-NH2-dGTP by Reverse Transcriptases and Mammalian DNA PolymerasesJournal of Biological Chemistry, 1997
- hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNACurrent Biology, 1996
- Bypass Replication of the Cisplatin-d(GpG) Lesion by Calf Thymus DNA Polymerase β and Human Immunodeficiency Virus Type I Reverse Transcriptase Is Highly MutagenicPublished by Elsevier ,1996
- GTBP, a 160-Kilodalton Protein Essential for Mismatch-binding Activity in Human CellsScience, 1995
- SPONTANEOUS MUTATIONAnnual Review of Genetics, 1991