Comparative analysis of GS and BK virus genomes

1 October 1979

journal article
research article
Published by American Society for Microbiology in Journal of Virology

Vol. 32 (1) , 220-225
https://doi.org/10.1128/jvi.32.1.220-225.1979

Abstract

Analysis of heteroduplexing between the genomes of GS virus, a BK-group virus, and the prototype BK virus revealed one region of nonhomology. Further analysis by cleavage of viral DNA with the restriction endonucleases EcoRI, HindIII, and HaeIII revealed that base changes in the GS virus genome spanned 0.6 to 0.7 map unit from the EcoRI site. Large T and small t antigens of GS virus appear to be similar in size to the BK virus antigens.

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