Pathological Manifestations in an Infant after Maternal Rubella in the Sixteenth Week of Gestation
- 10 September 1953
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 249 (11) , 439-442
- https://doi.org/10.1056/nejm195309102491103
Abstract
GREGG'S1 observation that rubella in the mother during early pregnancy frequently leads to congenital cataract of the unborn child has been confirmed by numerous investigators.2–4 The effects of the maternal infection on the conceptus vary within a broad range of possibilities: the fetus may escape injury, die or have various combinations of defects as late manifestations — arrested or distorted development of the eyes with anomalies of the teeth, middle ear and heart.2 Rubella is most likely to cause cataract (usually nuclear) when the infection occurs at the fourth to the sixth week of gestation.2, 5 The observation is consistent with . . .Keywords
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