Mechanism of substrate recognition by Hsp70 chaperones
- 1 August 2004
- journal article
- review article
- Published by Portland Press Ltd. in Biochemical Society Transactions
- Vol. 32 (4) , 617-621
- https://doi.org/10.1042/bst0320617
Abstract
The role of Hsp70 (heat-shock protein 70) chaperones in assisting protein-folding processes relies on their ability to associate with short peptide stretches of protein substrates in a transient and ATP-controlled manner. In the present study, we review the molecular details of the mechanism behind substrate recognition by Hsp70 proteins.Keywords
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