Hämoglobine, XXXIV. „Hämoglobin Heide“, ein neues embryonales Hämoglobin N-terminale Sequenz der δ-Ketten
- 1 January 1980
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 361 (2) , 1165-1170
- https://doi.org/10.1515/bchm2.1980.361.2.1165
Abstract
A new embryonic Hb is described. Erythrocytes of pig embryos were lysed. The lysate was analyzed by gel-electrophoresis and the Hb were separated on DEAE-Sephacel. The Hb fractions were characterized by sequence analysis. A new Hb chain.sbd..vtheta.-chain.sbd.not yet described was also found. The primary structure of the .vtheta.-chains is similar to that of the .epsilon.-chains. There are 3 differences in the 1st 30 residues. These .vtheta.-chains were associated with .zeta.-like chains and therefore AHb of the type X2/.vtheta.2 is proposed. The name Hb Heide is suggested for this new embryonic Hb. Four different globin genes (.alpha.-, .epsilon.-, .zeta.- and .vtheta.-genes) and 3 different Hb (Gower I, Gower II and Hb Heide) were detected in the embryonic respiration of mammals.This publication has 8 references indexed in Scilit:
- Molecular cloning of human epsilon-globin gene.Proceedings of the National Academy of Sciences, 1979
- HEMOGLOBINS .21. SEQUENCE-ANALYSIS OF PORCINE HEMOGLOBIN1978
- INTERACTION BETWEEN PHOSPHATE AND PROTEIN, AND RESPIRATION OF LLAMA, HUMAN FETUS AND HORSE1978
- Hämoglobin, XXIII. Notiz zur Sequenz der δ-Ketten der menschlichen Hämoglobine (Hb A2= α2/δ2)Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1978
- Hemoglobin Portland 1: A New Human Hemoglobin Unique in StructureScience, 1967
- The Amino Acid Sequence of the γ Chain of Human Fetal Hemoglobin*Biochemistry, 1963
- N-TERMINAL RESIDUES OF HUMAN FETAL HEMOGLOBINJournal of the American Chemical Society, 1958