Internalization and Transport of Mouse Beta-Interferon into the Cell Nucleus
- 1 June 1986
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Interferon Research
- Vol. 6 (3) , 241-245
- https://doi.org/10.1089/jir.1986.6.241
Abstract
An electron microscopic technique employing postembedding immunolabeling was used to identify unmodified, intracellular MuIFN-β molecules. The MuIFN-β was rapidly internalized by receptor-dependent endocytosis and within three minutes a majority of internalized MuIFN-β molecules was detected within the cell nucleus.Keywords
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