Variation in the Amount of Hemoglobin S in a Patient with Sickle Cell Trait and Megaloblastic Anemia
Open Access
- 1 April 1963
- journal article
- research article
- Published by American Society of Hematology in Blood
- Vol. 21 (4) , 479-483
- https://doi.org/10.1182/blood.v21.4.479.479
Abstract
A patient with sickle cell trait and nutritional megaloblastic anemia was found to have a much smaller proportion of hemoglobin S during the megaloblastic phase than after recovery. This observation suggests preferential synthesis of hemoglobin A by megaloblastic bone marrow in the presence of the A-S trait.Keywords
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