Pituitary Hormones and Contact Sensitivity in Rats
- 1 July 1983
- Vol. 38 (5) , 325-330
- https://doi.org/10.1111/j.1398-9995.1983.tb04126.x
Abstract
Hypophysectomized (Hypo‐X) rats do not develop contact sensitivity to dinitrochlorobenzene (DNCB). Daily treatment with prolactin or growth hormone completely restores the DNCB‐reactivity of Hypo‐X animals. Treatment of such animals with ACTH, FSH, LH, TSH or HCG has no restoring potential. Treatment with ACTH in addition to prolactin or growth hormone antagonizes restoration of Hypo‐X rats. These experiments indicate that the pituitary gland has the potential of regulating contact sensitivity.Keywords
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