Photodimer of Thymine in Ultraviolet-Irradiated DNA: Proof of Structure by X-ray Diffraction
- 28 June 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 160 (3835) , 1451-1452
- https://doi.org/10.1126/science.160.3835.1451
Abstract
Dimethylthymine was photodimerized with ultraviolet radiation, and the structure of one of the resulting dimers, the cis 5,5 : 6,6 isomer, was determined by single-crystal x-ray diffraction. This isomer is the same as that obtained by ultraviolet irradiation of DNA; hence the structure of the thymine dimer in irradiated DNA is now proved.Keywords
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