BLOOD PRESSURE STUDIES ON NORMAL AND VITAMIN E DEFICIENT RATS

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Abstract
Studies were made of the effect of prolonged vit. E deficiency on the systolic blood pressure of [female] rats. It was observed that 1 yr. old vit. E deficient rats showed a reduction of 29.4% in their blood pressure over the normal control animals. The mean pressure was 78.2 mm. Hg and 110.8 mm. Hg respectively. In those animals deprived of vit. E for a 2 yr. period no essential increase in the % difference occurred but a uniform reduction in blood pressure was noted. The normal and exptl. mean pressure readings were 87.2 mm. Hg and 61.7 mm. respectively. This reduction was due to an ageing effect and was not a manifestation of the dietary deficiency. Histolpgical examination of the vascular system of these animals failed to reveal any particular lesions that might explain this reduction in blood pressure. Others factors that influence the blood pressure of rats are room temp., age, sex, and methods used to determine blood pressure.

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