Substitution of Dietary Starch for Dextrose in Hyperlipemic Subjects.

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Abstract
Summary The comparative effects of dietary starch and dextrose on plasma tri-glyceride levels were studied on a metabolic ward in 2 lipemic patients. Plasma triglyc-erides were elevated when these subjects ingested a virtually fat free diet. Substitution of starch for the high dextrose formula produced no further change in plasma triglyc-erides. Caloric restriction in one patient resulted in a marked decrease in triglyceride even though he continued to eat an 85% carbohydrate, 15% protein formula. Both patients complained of a feeling of fullness and had trouble finishing an isocaloric high starch diet. These observations show that isocaloric starch diets did not decrease plasma triglycerides but that caloric restriction while a high carbohydrate diet is fed, will result in lower plasma triglyceride levels. They suggest that, unless careful supervision of dietary intake is maintained, the effects of carbohydrate substitutions in diet may be related to changes in caloric balance rather than to the type of carbohydrate ingested.