Nucleolar dominance in polytene cells of Drosophila
- 1 July 1983
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 80 (14) , 4427-4431
- https://doi.org/10.1073/pnas.80.14.4427
Abstract
Previous studies indicate that genes from only 1 of the cell''s nucleolus organizers undergo multiple rounds of DNA replication in polytene cells of Drosophila. This effect is shown here to be mediated by a function associated with the ribosomal genes of the dominant or replicating X chromosome. This function can act in trans to result in replication of the ribosomal genes on the recessive X chromosome in flies that are bobbed for the dominant X chromosome. In these cases, ribosomal genes from both chromosomes undergo polytenization. Heterochromatic regions that flank the nucleolus organizer have little or no effect on nucleolar dominance. In addition, deletion of the compensatory response (cr+) locus does not affect the dominance, suggesting that ribosomal gene compensation and nucleolar dominance in polytene cells of Drosophila are separate genetic phenomena.This publication has 15 references indexed in Scilit:
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