Clearance of Beta-2-Microglobulin Using Continuous Ambulatory Peritoneal Dialysis
- 1 January 1989
- journal article
- research article
- Published by S. Karger AG in Nephron
- Vol. 52 (4) , 352-355
- https://doi.org/10.1159/000185676
Abstract
In the 9 continuous ambulatory peritoneal dialysis (CAPD) patients studied, the mean clearance of β2-microglobulin was significantly higher using hypertonic as opposed to isotonic exchanges (1 ml/min and 0.75 ml/min, respectively). Clearance of β2-microglobulin correlated with the clearance of albumin. The daily mass transfer of β2-microglobulin ranged from 19 to 62 mg. Although all the daily production of β2-microglobulin is not eliminated in patients on CAPD their serum β2-microglobulin levels would be expected to be lower than in patients on haemodialysis. Long-term prospective studies are needed to determine whether lower serum β2-microglobulin levels lead to a lower incidence of dialysis amyloid.Keywords
This publication has 9 references indexed in Scilit:
- AMYLOID DEPOSITION IN SYSTEMIC ORGANS IN LONG-TERM HEMODIALYSIS-PATIENTS1987
- ULTRAFILTRATION WITH AN ISOSMOTIC SOLUTION DURING LONG PERITONEAL DIALYSIS EXCHANGESThe Lancet, 1987
- Dialysis arthropathy: amyloid or iron?BMJ, 1986
- Tumoral amyloidosis of bone of beta2-microglobulin origin in association with long-term hemodialysis: A new type of amyloid diseaseHuman Pathology, 1986
- Amyloid arthropathy in patients undergoing periodical haemodialysis for chronic renal failure: a new complication.Annals of the Rheumatic Diseases, 1985
- A new form of amyloid protein associated with chronic hemodialysis was identified as β2-microglobulinBiochemical and Biophysical Research Communications, 1985
- KINETICS OF CONTINUOUS AMBULATORY PERITONEAL-DIALYSIS (CAPD) WITH 4 EXCHANGES PER DAY1981
- Serum β2-Microglobulin in Hemodialyzed PatientsNephron, 1978
- Peritoneal Dialysis ClearancesNephron, 1978