Prevention of Stokes–Adams Seizures with Chlorothiazide

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Abstract
THIS report describes 8 patients with Stokes—Adams attacks who were seemingly benefited by chlorothiazide. My colleagues and I had been aware of the patient with isolated hypoaldosteronism who had very high levels of serum potassium and recurrent Stokes—Adams seizures.1 When the potassium level in this patient's serum was lowered with desoxycorticosterone, the attacks were relieved. It was reasoned that if the seizures could be relieved in that special situation by lowering of the plasma potassium concentration from above normal levels to normal, it might also be possible to alleviate the attacks associated with ordinary heart block by reduction of . . .

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