Inhibition of mast cell histamine release by 2,6-dimethoxy-p-benzoquinone isolated from Berchemia racemosa.
- 1 January 1986
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 34 (3) , 1333-1336
- https://doi.org/10.1248/cpb.34.1333
Abstract
The MeOH extract of Berchemia racemosa has an inhibitory activity on histamine release from rat mast cells. From the active fraction of the extract, 2,6-dimethoxy-p-benzoquinone was isolated. It shows strong inhibition of histamine release from rat mast cells induced by compound 48/80 and by concanavalin A, with IC50 values of 6 and 8 .mu.M, respectively.This publication has 1 reference indexed in Scilit: