The Value of the Glutaraldehyde and Formaldehyde Tests in Evaluation of the Globulin Level in Bovine Blood

Abstract
So-called liability reactions are based on the gelification of blood globulins when reacting with, i.e., glutaraldehyde or formaldehyde. Solidifying time is inversely proportional to the globulin concentration of the blood. In the present investigation glutaraldehyde and formaline-gelification tests were compared concerning their diagnostic and prognostic value in dairy cows with internal diseases. The investigation confirmed earlier results. The correlation between globulin concentration and gelification time was significant, and both tests give very good possibilities to reveal hyper-γ-globulinaemias. The 2 tests were relatively equal as regards the reliability. Even though the formol-gel reaction allows a somewhat better safety and semi-quantitative differentiation than the glutaraldehyde test, the latter has obvious practical advantages. It can be done on whole blood and with a short observation time. Thus, the blood globulin status can be evaluated during the visit on the farm.

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