Clinical experience with metolazone in fifty-two African patients: synergy with frusemide

Abstract
Summary: The use of metolazone (Zaroxolyn), a new diuretic, in fifty-two African patients is described. The drug was found to be safe and moderately effective when used alone, but combined with frusemide it proved to be of great value in patients whose fluid retention was refractory to other diuretics.