Duchenne Dystrophy: Alteration in Muscle Plasma Membrane Structure
- 27 May 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 196 (4293) , 1005-1007
- https://doi.org/10.1126/science.860127
Abstract
Freeze fracture studies of skeletal muscle from eight patients with Duchenne dystrophy showed nonuniform distribution and depletion of particles on both protoplasmic and extracellular faces of the muscle plasma membrane. The findings support the view that the muscle surface membrane is abnormal in this disorder and indicate that alterations are present in the internal molecular architecture of the membrane.This publication has 12 references indexed in Scilit:
- Duchenne dystrophyNeurology, 1975
- Segmental fibre breakdown and defects of the plasmalemma in diseased human musclesActa Neuropathologica, 1975
- STUDIES OF EXCITABLE MEMBRANESThe Journal of cell biology, 1974
- Adenyl Cyclase in Normal and Pathologic Human MuscleArchives of Neurology, 1974
- Chemical Characterization and Surface Orientation of the Major Glycoprotein of the Human Erythrocyte MembraneProceedings of the National Academy of Sciences, 1972
- Membrane Formation by the Adenosine Triphosphatase of Sarcoplasmic ReticulumJournal of Biological Chemistry, 1971
- Lamellar and hexagonal lipid phases visualized by freeze-etchingBiochimica et Biophysica Acta (BBA) - Biomembranes, 1970
- ULTRASTRUCTURE OF SARCOPLASMIC RETICULUM PREPARATIONSThe Journal of cell biology, 1969
- Fracture faces of frozen membranes.Proceedings of the National Academy of Sciences, 1966
- BIOCHEMICAL STUDY OF MUSCLE IN PROGRESSIVE MUSCULAR DYSTROPHY 1Journal of Clinical Investigation, 1954