Comparison of fluconazole and amphotericin B in treating histoplasmosis in immunosuppressed mice
Open Access
- 1 December 1987
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 31 (12) , 2005-2006
- https://doi.org/10.1128/aac.31.12.2005
Abstract
Fluconazole (UK-49,858) was compared with amphotericin B in treating histoplasmosis in female AKR mice immunosuppressed with either cyclophosphamide or cortisone. Both drugs protected animals from a lethal challenge with Histoplasma capsulatum, but neither regimen resulted in cures since viable organisms were cultured from spleens of survivors.This publication has 13 references indexed in Scilit:
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