Induction of labour by prostaglandin pessaries or oxytocin infusion after spontaneous rupture of membranes

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Abstract
Expectant management in the presence of spontaneous rupture of the membrane in late pregnancy has generally been replaced by active intervention in most modern obstetric units. Stimulation of contractions is started as soon as the fetus is assessed to be sufficiently mature. Once the membranes have ruptured there is a portal of entry for infection and the longer this situation exists, the higher the risk of infection. Intra-uterine infections after rupture of membranes affect 10 per cent of pregnancies within 48 hours (Fayez, 1978). Perinatal mortality rate doubles when the latent interval exceeds 24 hours and quadruples after 48 hours (Burchell, 1964).

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