Mechanisms of Troglitazone Hepatotoxicity

This publication has 28 references indexed in Scilit:

• The Mechanisms of Action of PPARs
  Annual Review of Medicine, 2002
• Diabetic KKAy mice exhibit increased hepatic PPARγ1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones
  Published by Elsevier ,2001
• Characterization of UDP-glucuronosyltransferases (UGTs) involved in the metabolism of troglitazone in rats and humans.
  The Journal of Toxicological Sciences, 2000
• Acute troglitazone action in isolated perfused rat liver
  British Journal of Pharmacology, 1999
• Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas
  Journal of Clinical Investigation, 1999
• Death Receptors in Liver Biology and Pathobiology
  Hepatology, 1999
• Hepatotoxicity in drug development: detection, significance and solutions
  Journal of Hepatology, 1997
• Comparative hepatotoxicity of cholic acid, deoxycholic acid and lithocholic acid in the rat: in vivo and in vitro studies
  Toxicology Letters, 1992
• Zonation of cytochrome P450 isozyme expression and induction in rat liver
  European Journal of Biochemistry, 1992
• Non‐alcoholic steatohepatitis: Impaired antipyrine metabolism and hypertriglyceridaemia may be clues to its pathogenesis
  Journal of Gastroenterology and Hepatology, 1991