VARIATIONS IN UPTAKE AND EXCRETION OF RADIOIODINE IN THE RAT FOLLOWING DIFFERENT MODES OF ADMINISTRATION

Publisher Website
Google Scholar
Abstract
SUMMARY: The variations in uptake and excretion of radio-iodine following: (a) intraperitoneal, (b) intravenous, (c) intramuscular, (d) subcutaneous injection as well as oral administration with (e) empty stomach, and (f) full stomach, have been investigated. There is a significant difference in the uptake of radio-iodine (131I) only during the first few hours after administration. The maximum uptake of 131I occurs within 24 hr, and is independent of the mode of administration. There is no significant difference in the uptake of 131I after 24 hr. The excretion of 131I in the urine also showed no significant difference during the period of observation (1–8 days).