Metabolic cycles as an underlying basis of biological oscillations
- 5 July 2006
- journal article
- review article
- Published by Springer Nature in Nature Reviews Molecular Cell Biology
- Vol. 7 (9) , 696-701
- https://doi.org/10.1038/nrm1980
Abstract
What is the driving force behind periodic biological oscillations such as the circadian, hibernation and sleep–wake cycles? Temporal compartmentalization of metabolism has been shown in budding yeast, and might form the underlying basis for many of the rhythmic phenomena in biology. The evolutionary origins of periodic phenomena in biology, such as the circadian cycle, the hibernation cycle and the sleep–wake cycle, remain a mystery. We discuss the concept of temporal compartmentalization of metabolism that takes place during such cycles, and suggest that cyclic changes in a cell's metabolic state might be a fundamental driving force for such biological oscillations.Keywords
This publication has 53 references indexed in Scilit:
- Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular ProcessesScience, 2005
- Coordinated Transcription of Key Pathways in the Mouse by the Circadian ClockCell, 2002
- Circadian Regulation of Gene Expression Systems in the Drosophila HeadNeuron, 2001
- Microarray Analysis and Organization of Circadian Gene Expression in DrosophilaCell, 2001
- Orchestrated Transcription of Key Pathways in Arabidopsis by the Circadian ClockScience, 2000
- Oscillatory metabolism ofSaccharomyces cerevisiaein continuous cultureFEMS Microbiology Letters, 1992
- Oscillatory reductions of pyridine nucleotides during anaerobic glycolysis in brewers' yeastArchives of Biochemistry and Biophysics, 1964
- CONTROL OF THE WAVEFORM OF OSCILLATIONS OF THE REDUCED PYRIDINE NUCLEOTIDE LEVEL IN A CELL-FREE EXTRACTProceedings of the National Academy of Sciences, 1964
- DAMPED SINUSOIDAL OSCILLATIONS OF CYTOPLASMIC REDUCED PYRIDINE NUCLEOTIDE IN YEAST CELLSProceedings of the National Academy of Sciences, 1964
- Oscillations of glycolytic intermediates in yeast cellsBiochemical and Biophysical Research Communications, 1964