Application of the Bivalent Ligand Approach to the Design of Novel Dimeric Serotonin Reuptake Inhibitors

This publication has 12 references indexed in Scilit:

• Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. Potent Dopamine and Serotonin Reuptake Inhibitors
  Journal of Medicinal Chemistry, 2000
• Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors
  Angewandte Chemie International Edition in English, 1998
• The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments
  Brain Research Reviews, 1997
• Discovering High-Affinity Ligands for Proteins: SAR by NMR
  Science, 1996
• Serotonin Dimers: Application of the Bivalent Ligand Approach to the Design of New Potent and Selective 5-HT_1B/1D Agonists
  Journal of Medicinal Chemistry, 1996
• Synthesis and 5HT Modulating Activity of Stereoisomers of 3-Phenoxymethyl-4-phenylpiperidines.
  Acta Chemica Scandinavica, 1996
• Prozac (fluoxetine, lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: Twenty years since its first publication
  Life Sciences, 1995
• Bivalent indoles exhibiting serotonergic binding affinity
  Bioorganic & Medicinal Chemistry Letters, 1995
• Narcotic antagonistic potency of bivalent ligands which contain .beta.-naltrexamine. Evidence for simultaneous occupation of proximal recognition sites
  Journal of Medicinal Chemistry, 1982
• On the attribution and additivity of binding energies
  Proceedings of the National Academy of Sciences, 1981