Lack of effect of butylated hydroxytoluene on dimethylhydrazine-induced colon carcinogenesis in rats
- 1 February 1979
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 35 (2) , 257-258
- https://doi.org/10.1007/bf01920650
Abstract
Rats were given 6600 ppm of butylated hydroxytoluene (BHT) in the diet along with 10 weekly oral doses of dimethylhydrazine (DMH, 30 mg/kg). The incidence and mean number of colonic tumors produced were similar to that of rats given DMH alone. Thus, BHT did not provide any protective effect against colon carcinogenesis.Keywords
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