Biosynthesis of anthracyclinones
- 10 January 1988
- journal article
- Published by Wiley in Journal of Basic Microbiology
- Vol. 28 (1-2) , 137-144
- https://doi.org/10.1002/jobm.3620280117
Abstract
Recent biosynthetic studies confirmed that anthraquinones are involved as intermediates in the pathway to anthracyclines. The present knowledge in this field has been reviewed. Furthermore, a new generalized order of biosynthetic intermediates from the hypothetical polyketide to aklavinone and related anthracyclinones has been proposed involving tricyclic precursors and 7‐hydroxy‐naphthacenequinones, which also have been found in mutants of anthracycline‐producing strains.Keywords
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