Abstract
To present a reconceptualization of fatigue. Studies indexed in CINAHL, MEDLINE, PubMed, Psyc INFO, SPORTDiscus, and CancerLit from 1995-2004; studies included in the bibliographies of indexed articles; and five qualitative studies conducted by the author. Tiredness and exhaustion are conceptually distinct from fatigue. All three concepts are located along an adaptational continuum in a manner consistent with stress theory. Interventions should focus on the elimination or reduction of stressors and the increase of patients' resistance to stressors. Interventions that prevent or delay progression from tiredness to fatigue will be different from those that prevent or delay progression from fatigue to exhaustion.

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