Early Embryonic Lethality Caused by Targeted Disruption of the 3-Hydroxy-3-methylglutaryl-CoA Reductase Gene
Open Access
- 1 October 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (44) , 42936-42941
- https://doi.org/10.1074/jbc.m307228200
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E.Journal of Clinical Investigation, 1998
- Developmental toxicity of the HMG‐CoA reductase inhibitor, atorvastatin, in rats and rabbitsTeratology, 1994
- Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.Journal of Clinical Investigation, 1993
- HMG‐CoA reductase mRNA in the post‐implantation rat embryo studied by in situ hybridizationTeratology, 1993
- Regulation of the mevalonate pathwayNature, 1990
- Somatic cell genetics and the study of cholesterol metabolismBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1988
- Mevalonate supplementation in pregnant rats suppresses the teratogenicity of mevinolinic acid, an inhibitor of 3‐hydroxy‐3‐methylglutaryl‐coenzyme a reductaseTeratology, 1983
- Preimplantation mouse embryos synthesize membrane sterolsDevelopmental Biology, 1982
- Inhibitory Effects on Lipid Metabolismn in Cultured Cells of ML‐236B, a Potent Inhibitor of 3‐Hydroxt‐3‐methylglutaryl‐Cornzyme‐A ReductaseEuropean Journal of Biochemistry, 1978
- Diurnal variation and cholesterol regulation of hepatic HMG-CoA reductase activityBiochemical and Biophysical Research Communications, 1969