Androgen sulphate formation in male and female rats
- 1 January 1968
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 106 (2) , 497-501
- https://doi.org/10.1042/bj1060497
Abstract
1. After large doses of androsterone, epiandrosterone, dehydroepiandrosterone and testosterone, female rats excreted more of the dose conjugated with sulphuric acid than did the males. 2. Androgens were also incubated with liver slices from male and female rats. Slices from females conjugated androgens with sulphuric acid to a greater extent than did slices from males. 3. The amount of unchanged androgen present in the faeces of orally dosed animals was 4–35% of the dose.This publication has 19 references indexed in Scilit:
- Substrate and inhibitor specificity of the cholesterol oxidase in bovine adrenal cortexBiochemical Journal, 1966
- THE METABOLISM OF PROGESTERONE BY ANIMAL TISSUES IN VITRO. SEX AND SPECIES DIFFERENCES IN CONJUGATE FORMATION DURING THE METABOLISM OF (4-14C)PROGESTERONE BY LIVER HOMOGENATESBiochemical Journal, 1965
- Evidence that Steroid Sulfates Serve as Biosynthetic Intermediates. II. In Vitro Conversion of Pregnenolone-3H Sulfate-35S to 17α-Hydroxypregnenolone-3H Sulfate-35S*Biochemistry, 1964
- The 16α-hydroxylation of dehydroepiandrosterone (3β-hydroxyandrost-5-en-17-one) by rat-liver slicesBiochemical Journal, 1962
- The effect of development on the composition of a long bone of the pig, rat and fowlBiochemical Journal, 1962
- SEX DIFFERENCE IN RATE OF RING A REDUCTION OF Δ4-3-KETO-STEROIDSIN VITROBY RAT LIVER12Endocrinology, 1958
- Steroid 4-Hydrogenases of Rat Liver.Experimental Biology and Medicine, 1958
- Comparative studies on the liver sulphatasesBiochemical Journal, 1958
- SEX DIFFERENCES IN ORIENTATION OF REDUCTION PRODUCTS OF 3-KETO-C19 STEROIDS BY RAT LIVER HOMOGENATESJournal of Biological Chemistry, 1957
- The enzymic synthesis of steroid sulphatesBiochemical Journal, 1956