The Mycobacterium-Specific Gene Rv2719c Is DNA Damage Inducible Independently of RecA
- 15 August 2006
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 188 (16) , 6034-6038
- https://doi.org/10.1128/jb.00340-06
Abstract
The mycobacterium-specific gene Rv2719c was found to be expressed primarily from a promoter that was clearly DNA damage inducible independently of RecA. Upstream of the transcriptional start site for this promoter, sequence motifs resembling those observed previously at the RecA-independent, DNA damage-induciblerecApromoter were identified, and the −10 motif was demonstrated by mutational analysis in transcriptional fusion constructs to be important for expression of Rv2719c.Keywords
This publication has 26 references indexed in Scilit:
- Transcription activation of a UV‐inducible Clostridium perfringens bacteriocin gene by a novel σ factorMolecular Microbiology, 2005
- Identification of a promoter motif regulating the major DNA damage response mechanism ofMycobacterium tuberculosisFEMS Microbiology Letters, 2004
- Identification of a promoter motif regulating the major DNA damage response mechanism ofFEMS Microbiology Letters, 2004
- Characterization of the Two Mycobacterium tuberculosis recA PromotersJournal of Bacteriology, 2003
- DNA damage induction of recA in Mycobacterium tuberculosis independently of RecA and LexAMolecular Microbiology, 2002
- Definition of the Mycobacterial SOS Box and Use To Identify LexA-Regulated Genes inMycobacterium tuberculosisJournal of Bacteriology, 2002
- Identification of Some DNA Damage-Inducible Genes of Mycobacterium tuberculosis : Apparent Lack of Correlation with LexA BindingJournal of Bacteriology, 2001
- Characterization of Mycobacterium tuberculosis LexA: recognition of a Cheo (Bacillus-type SOS) boxMicrobiology, 1997
- The expression of the Acinetobacter calcoaceticus recA gene increases in response to DNA damage independently of RecA and of development of competence for natural transformationMicrobiology, 1996
- The SOS regulatory system of Escherichia coliCell, 1982