HLA‐DR antigens in gold‐induced neutropenia
- 1 December 1986
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 29 (12) , 1515-1517
- https://doi.org/10.1002/art.1780291214
Abstract
We studied the clinical courses of 9 patients who developed acute gold-induced neutropenia with marrow aplasia. Eight of these carried HLA-DR4, compared with only 2 of 9 who had mild, chronic, isolated neutropenia (P < 0.05). Only 1 of 9 patients with myelotoxicity carried HLA-DR3. We conclude that these groups are immunogenetically distinct, and that HLA-DR3 is not a significant risk factor for severe gold-induced neutropenia.This publication has 7 references indexed in Scilit:
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