INTERACTION OF PLASMA FIBRONECTIN WITH SELECTED CRYOGLOBULINS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 40  (2) , 358-364
Abstract
Plasma fibronectin (PFN) is associated with polyclonal cryoglobulins. Cryoglobulins from 2 patients with essential mixed cryoglobulinemia were analyzed immunoelectrophoretically to determine a possible association between PFN and immunoglobulin [Ig] complexes in the formation of cryoprecipitates. In cryoglobulins from each patient, distinctive alterations in electrophoretic migration patterns of PFN and Ig were associated with the formation of a cryoprecipitate. PFN apparently binds to some serum component in the process of cryoglobulin formation; that component may be Ig.