Control of nucleic acid charge on the X -chromosome of the hamster
- 7 August 1946
- journal article
- research article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 133 (872) , 313-326
- https://doi.org/10.1098/rspb.1946.0015
Abstract
When its nucleic acid charge is reduced, the differential segment of the X-chromosome of Cricetus auratus (golden hamster) appears as a thin, un-spiralized, understained thread (starved cells). This occurs in conditions lowering spermatogenesis and is proportional to decrease in spermatogenesis. Summer level (breeding season) of starved cells varied from 10% at age 6 months to 30% at age 24 months. Winter level of starved cells varied from 50% at age 6 months to 70% at age 24 months. With 17 to 119 days deficient diet, summer level of starved cells increased to 50 to 85%. In 3 cases of disease (scabies, liver pathology, general debility), summer level of starved cells ranged from 26 to 87%. Results are explained on the basis of deficient cytoplasmic stores of ribose nucleic acid.Keywords
This publication has 17 references indexed in Scilit:
- Triurol in Cerebral AngiographyActa Radiologica, 1955
- Effect of Dietary Protein on Liver CytoplasmNature, 1944
- Tissue nucleic acidsBiochemical Journal, 1944
- ORIGIN OF MALIGNANT TUMOUR CELLSNature, 1943
- Heterochromatin in TritonProceedings of the Royal Society of London. B. Biological Sciences, 1942
- CHROMOSOME CHEMISTRY AND GENE ACTIONNature, 1941
- Morbid mitosis and the activity of inert chromosomes in sorghumProceedings of the Royal Society of London. B. Biological Sciences, 1941
- THE DETECTION OF INERT GENESJournal of Heredity, 1941
- Pentose Nucleotides in the Cytoplasm of Growing TissuesNature, 1939
- Differential Reactivity of the ChromosomesAnnals of Botany, 1938