The biochemical effects of CPDA‐2‐drawn red blood cells of delayed refrigeration prior to component preparation
- 12 November 1982
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 22 (6) , 485-487
- https://doi.org/10.1046/j.1537-2995.1982.22683068608.x
Abstract
The effects of an 8-h hold at 22.degree. C prior to component preparation were evaluated in a split-bag study using 9 U of blood preserved in citrate-phosphate-dextrose-adenine (CPDA-2). Each unit was divided in half, platelet-rich plasma removed at 0 or 8 h, respectively, and the half units of red blood cells stored at 4.degree. C for 42 days. The only red blood cell metabolic differences seen in the bags held 8 h (compared to those not held) were a 21% rise in ATP, which was not significant after 14 days of storage, and a 33% loss of 2,3-diphosphoglycerate which resulted in a loss curve similar to that seen with acid-citrate-dextrose blood. The logistic advantages seem to warrant an 8-h holding period for red blood cells drawn in CPDA-2.This publication has 7 references indexed in Scilit:
- In vivo viability of red blood cells stored in CPDA‐2Transfusion, 1982
- An in vivo comparison of CPD and CPDA‐2 preserved platelet concentrates after an 8‐hour preprocess hold of whole bloodTransfusion, 1982
- Adenine Blood PreservationCRC Critical Reviews in Clinical Laboratory Sciences, 1981
- The In Vitro Evaluation of Modifications in CPD‐Adenine Anticoagulated‐Preserved Blood at Various HematocritsTransfusion, 1980
- Effects of Prolonged Room Temperature Holding of Whole Blood Intended for Preparation of ComponentsTransfusion, 1979
- The Effect of Delayed Refrigeration on Red Blood Cells, Platelet Concentrates and Cryoprecipitable AHFTransfusion, 1978
- Effect of initial storage at room temperature on human red blood cell ATP, 2,3‐DPG, and viabilityTransfusion, 1977