Polymer Side-Chain Degradation as a Tool to Control the Destabilization of Polyplexes
- 1 January 2004
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 21 (1) , 170-176
- https://doi.org/10.1023/b:pham.0000012165.68765.e6
Abstract
Purpose. We purposed to design a cationic polymer that binds to pDNA to form polyplexes and that subsequently degrades within a few days at physiological pH and temperature, releasing the DNA in the...Keywords
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