Genetic support for a quantitative trait nucleotide in the ABCG2 gene affecting milk composition of dairy cattle
Open Access
- 21 June 2007
- journal article
- Published by Springer Nature in BMC Genomic Data
- Vol. 8 (1) , 32
- https://doi.org/10.1186/1471-2156-8-32
Abstract
Our group has previously identified a quantitative trait locus (QTL) affecting fat and protein percentages on bovine chromosome 6, and refined the QTL position to a 420-kb interval containing six genes. Studies performed in other cattle populations have proposed polymorphisms in two different genes (ABCG2 and OPN) as the underlying functional QTL nucleotide. Due to these conflicting results, we have included these QTNs, together with a large collection of new SNPs produced from PCR sequencing, in a dense marker map spanning the QTL region, and reanalyzed the data using a combined linkage and linkage disequilibrium approach.Keywords
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