XXVIII Histology of the Monkey Labyrinth following Experimental Cryosurgery

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Abstract
The temporal bone sections from 12 monkeys exposed to experimental cryosurgery were studied by light microscopy. Although the nystagmus response to caloric stimulation was eliminated completely in 10 animals, the sensory epithelia, supporting structures and nerve fibers of the cristae, maculae and cochleae appeared normal in 7 animals. Mild autolysis was observed in 4 animals but was due to poor perfusion in 2 cases and death before fixation in 2 cases. Severe inner ear damage in one animal cannot be explained. The only pathological condition common to all animals was the presence of dense connective tissue within the horizontal semicircular canal at the site of cryosurgery. The loss of nystagmus response following cryosurgery may be due to something other than mechanical blockage of the horizontal semicircular canal.

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