Doxepin Plasma Concentrations in Clinical Practice Could There Be a Pharmacokinetic Explanation for Low Concentrations?
- 1 January 1985
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 10 (4) , 365-370
- https://doi.org/10.2165/00003088-198510040-00006
Abstract
During therapeutic use of doxepin, we have often observed unexpectedly low doxepin plasma concentrations in patients on moderate dosages, e.g. 100 to 200mg daily. While non-compliance seemed the most...This publication has 9 references indexed in Scilit:
- Nonlinear desipramine pharmacokinetics: a case study.1985
- Nortriptyline capacity-limited metabolism: a case report.1984
- Apparent nonlinear kinetics of secondary-amine tricyclic antidepressants.1983
- Desipramine Plasma Concentration and Antidepressant ResponseArchives of General Psychiatry, 1982
- Doxepin plasma levels and therapeutic response in depression: preliminary findings.1982
- Clomipramine and Doxepin in Depressive NeurosisArchives of General Psychiatry, 1980
- The clinical application of tricyclic antidepressant pharmacokinetics and plasma levelsAmerican Journal of Psychiatry, 1980
- CLINICAL IMPORTANCE OF DOXEPIN ANTIDEPRESSANT PLASMA-LEVELS1978
- Treatment of depression with tricyclic drugs--pharmacokinetic and pharmacodynamic aspects.1976