Localization of chromosomal protein HMG-1 in polytene chromosomes of Chironomus thummi.

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Abstract
The distribution of accessible antigenic sites in the chromosomal protein high motility group one (HMG-1) in Chironomus thummi polytene chromosomes is visualized by immunofluorescence. HMG-1 is distributed in a distinct banding pattern along the entire length of the chromosomes. The banding pattern obtained with fluorescent antibody does not strictly correspond to that observed by phase-contrast microscopy. The amount of HMG-1 increases and the fluorescent banding pattern changes during the development of the organism. Apparently, the protein may be involved in modulation of the structure of selected loci in the chromosome.