Pepsin Secretion and Synthesis in vitro

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Abstract
Pepsin secretion and synthesis by mouse stomachs were studied in vitro. There is a basal rate of secretion, and carbaminoylcholine stimulates further secretion. At the optimal drug concn. of 0.1 mg. % the rate of secretion is 300% of the basal rate. Atropine inhibits the additional secretion caused by the drug but not the basal secretion. The stomachs were supplied with amino acid mixtures, but no evidence of pepsin synthesis was found.

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