Evolution of a series of non-quinoline leukotriene D4 receptor antagonist; synthesis and sar of benzothiazoles and thiazoles substituted benzyl alcohols as potent LTD4 antagonists
- 3 August 1995
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 5 (15) , 1615-1620
- https://doi.org/10.1016/0960-894x(95)00265-u
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- The discovery of L-699,392, a novel potent and orally active leukotriene D4 receptor antagonistBioorganic & Medicinal Chemistry Letters, 1994
- Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects.Thorax, 1993
- The discovery of a new structural class of potent orally active leukotriene D4 antagonistsBioorganic & Medicinal Chemistry Letters, 1992
- Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjectsThe Lancet, 1991
- 677 The therapeutic effects of MK-571, a potent and selective leukotriene (LT) D4 receptor antagonist, in patients with chronic asthmaJournal of Allergy and Clinical Immunology, 1991
- 2 The effect of the leukotriene D4 (LTD4) antagonist SKF 104353 on aspirin-induced asthmaJournal of Allergy and Clinical Immunology, 1991
- Inhibition of Exercise-Induced Bronchoconstriction by MK-571, a Potent Leukotriene D4–Receptor AntagonistNew England Journal of Medicine, 1990
- An efficient and catalytically enantioselective route to (S)-(-)-phenyloxiraneThe Journal of Organic Chemistry, 1988
- A stable and easily prepared catalyst for the enantioselective reduction of ketones. Applications to multistep synthesesJournal of the American Chemical Society, 1987
- Effects of a 5-lipoxygenase inhibitior (L-651,392) on primary and late pulmonary responses to ascaris antigen in the squirrel monkeyInflammation Research, 1987