Effects of d-amphetamine, maprotiline, l-dopa, and haloperidol on the components of the predatory behavior of the ferret, Putorius furo l.
- 1 September 1979
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 64 (3) , 355-359
- https://doi.org/10.1007/bf00427524
Abstract
Ferret predation on rats was examined in an arena. One hour before the test one of the following drugs was administered: d-Amphetamine (0.8 and 1.4 mg/kg IM), maprotiline (10 and 40 mg/kg orally), l-dopa (30 and 60 mg/kg orally), or haloperidol (0.14 and 0.6 mg/kg IM). Provided that capture was successful, the sequence of the behavioral components was not changed by these drugs. With the exceptions of paw movements and rolling over, which were not affected by the drugs, the components of predatory behavior were influenced differently. This leads to the assumption that a drug affects different mechanisms which control behavior. It is assumed that dopamine is involved in the control of capture elicitation as well as in the control of pursuit and biting. Capture elicitation was inhibited by d-amphetamine and l-dopa, but not by maprotiline, and was even facilitated by haloperidol. The orientation of pursuit movements and biting was impaired by l-dopa and improved by haloperidol, whereas maprotiline did not influence these components.This publication has 21 references indexed in Scilit:
- Chlorimipramine inhibition of muricide: the role of the ascending 5-HT projectionBrain Research, 1978
- Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral SupersensitivityScience, 1977
- Noradrenaline synthesis from L-DOPA in rodents and its relationship to motor activityPharmacology Biochemistry and Behavior, 1976
- Effects of imipramine, d-amphetamine, and tripelennamine on mouse and frog killing by the ratPhysiology & Behavior, 1976
- Para-chlorophenylalanine, serotonin and killing behaviorPharmacology Biochemistry and Behavior, 1975
- Inhibitory effects of pre- and posttest drugs on mouse-killing by ratsPharmacology Biochemistry and Behavior, 1975
- Initiation of mouse killing in non-killer rats by repeated pilocarpine treatmentPhysiology & Behavior, 1972
- Evidence for Inhibition by Brain Serotonin of Mouse Killing Behaviour in RatsNature, 1971
- Structural relationship and potency of agents which selectively block mouse killing (muricide) behavior in ratsLife Sciences, 1969
- Effects of drugs on the mouse-killing (muricide) test and its relationship to amygdaloid functionInternational Journal of Neuropharmacology, 1966