EFFECT OF OROTIC ACID UPON SERUM BILIRUBIN IN NEWBORN INFANTS WITH ERYTHROCYTE G‐6‐PD DEFICIENCY
- 21 January 1974
- journal article
- Published by Wiley in Acta Paediatrica
- Vol. 63 (1) , 143-146
- https://doi.org/10.1111/j.1651-2227.1974.tb04363.x
Abstract
Summary: Fifty mature male newborns with erythrocyte G‐6‐PD deficiency were used for a study con cerning the effectiveness of orotic acid in preventing severe hyperbilirubinemia. Twentyfive randomly selected neonates were given orotic acid (100 mg/kg/day) orally in two daily doses from their 1st to their 5th day of life. Twenty‐five newborns were not treatedAccording to these results orotic acid does not seem to be effective in preventing severe hyperbilirubinemia, which frequently occurs in newborn babies' with erythrocyte G‐6‐PD deficiency. and served as controls. Six exchange transfusions were performed in the test group and six in the controls.Keywords
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