Zinc and micronutrient supplements for children
Open Access
- 1 August 1998
- journal article
- review article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 68 (2) , 495S-498S
- https://doi.org/10.1093/ajcn/68.2.495s
Abstract
Provision of zinc supplements to children should be considered when their usual diet is low in absorbable zinc; severe stunting, low plasma zinc, or both; or persistent diarrhea. Inadequate zinc intakes are highly prevalent in developing countries, especially during the period of complementary feeding when zinc requirements are high and breast milk contributes little. To date, systematic evaluation of the acceptability of different zinc salts used as supplements is lacking. Some zinc salts are unpalatable and cause problems, such as nausea, at higher doses. Zinc carbonate and oxide are insoluble and poorly absorbed. Little information on the bioavailability of different zinc supplements in the presence of dietary inhibitors of zinc absorption exists. More information is needed on the quantity and frequency of dosing. Consideration should be given to the routine inclusion of zinc in iron supplements provided to children and to the simultaneous inclusion of other micronutrients in zinc supplements.Keywords
This publication has 28 references indexed in Scilit:
- Use of zinc tolerance test and 24-hour urinary zinc content to assess oral zinc absorption.Journal of the American College of Nutrition, 1996
- Zinc absorption in adult humans: the effect of iron fortificationBritish Journal of Nutrition, 1995
- Effect of Intragastric pH on the Absorption of Oral Zinc Acetate and Zinc Oxide in Young Healthy VolunteersJournal of Parenteral and Enteral Nutrition, 1995
- Zinc changes in blood and urine during cyclic pareteral nutrition: relationships with amino acid metabolismBritish Journal of Nutrition, 1994
- Zinc Nutrition in Developing CountriesNutrition Research Reviews, 1994
- Absorption of zinc sulfate, methionine, and polyascorbate in the presence and absence of a plant-based rural mexican dietNutrition Research, 1993
- Zinc supplements in breastfed infantsThe Lancet, 1992
- Dose dependence of zinc and manganese absorption in manProceedings of the Nutrition Society, 1992
- Absorption and metabolism of oral zinc gluconate in humans in fasting state, during, and after a mealBiological Trace Element Research, 1992
- Apparent zinc absorption by rats from foods labelled intrinsically and extrinsically with 67ZnBritish Journal of Nutrition, 1991