Three-dimensional mapping of the sweet taste receptor site
- 31 October 1978
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 21 (11) , 1154-1158
- https://doi.org/10.1021/jm00209a013
Abstract
The active sites of the receptors for sweet and bitter tastants were related by a simple symmetry operation. This relationship allowed the identification of the critical geometrical features of both receptor sites. The model proposed for the sweet site was consistent with a large number of (conformationally rigid) sweet molecules.This publication has 2 references indexed in Scilit:
- Interaction of .alpha.-L-aspartyl-L-phenylalanine methyl ester with the receptor site of the sweet taste budJournal of the American Chemical Society, 1976
- Molecular Theory of Sweet TasteNature, 1967