HISTOLOGICAL CHANGES IN HUMAN LIVER BIOPSIES FROM CHRONIC ALCOHOLICS

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Abstract
In a material consisting of liver biopsies from 330 consecutive patients with chronic alcoholism (alcohol consumption of more than 50 g/day for a period of greater duration than a year) 60 (18 per cent) show cirrhosis or have given a suspicion of cirrhosis. 56 of these in addition exhibit varying degrees of fatty change. 212 biopsies (64 per cent) show fatty change without cirrhosis. 23 (seven per cent) biopsies as the most important pathological finding exhibit varying degrees of iron storage in the liver cells, and 27 biopsies (eight per cent) show normal liver tissue without iron content and without a single cell with fatty change. The last eight biopsies show hepatitis or non specific reactive changes.

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