GLOMERULAR FILTRATION RATE AND RENAL PLASMA FLOW IN ACROMEGALY

Abstract
Measurements of the glomerular filtration rate (GFR), renal plasma flow and body water compartments were performed in 13 patients with acromegaly and 22 normal subjects. The values for the GFR were higher in the acromegalics, relative to body surface area, total body water and intracellular water. The values for the renal plasma flow in the acromegalics were higher in relation to the intracellular water and probably higher in relation to the body surface area, as compared to normal subjects. It was concluded that in acromegaly there were parallel change in the GFR renal plasma flow and extracellular water.