Persistent reactivable latent herpes simplex virus infection in trigeminal ganglia of mice treated with antiviral drugs
- 1 March 1981
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 69 (1) , 43-48
- https://doi.org/10.1007/bf01315264
Abstract
Latent reactivable infection was established with HSV in mouse trigeminal ganglion. A number of antiviral drugs (IUDR, acycloguanosine, Ara-A, PAA and PFA), effective against acute CNS infection with HSV, failed to influence the latent infection once established. Neither lipophilic properties of PFA-derivatives nor the combination of Ara-A and acyloguanosine improved the drug-effects on HSV latency.This publication has 22 references indexed in Scilit:
- Latent herpes simplex virus trigeminal ganglionic infection in mice and demyelination in the central nervous systemJournal of the Neurological Sciences, 1979
- Latent infections of sensory ganglia as influenced by phosphonoformate treatment of herpes simplex virus-induced skin infections in hairless miceAntimicrobial Agents and Chemotherapy, 1979
- Effect of Acycloguanosine Treatment on Acute and Latent Herpes Simplex Infections in MiceAntimicrobial Agents and Chemotherapy, 1979
- Treatment of Experimental Herpesvirus Infections with Phosphonoformate and Some Comparisons with PhosphonoacetateAntimicrobial Agents and Chemotherapy, 1978
- Therapeutic Effect of Trisodium Phosphonoformate on Cutaneous Herpesvirus Infection in Guinea PigsAntimicrobial Agents and Chemotherapy, 1978
- Latent Herpes Simplex Virus Infections in Sensory Ganglia of Mice After Topical Treatment with Adenine Arabinoside and Adenine Arabinoside MonophosphateAntimicrobial Agents and Chemotherapy, 1977
- Treatment of Infections Due to Herpesvirus in Humans: A Critical Review of the State of the ArtThe Journal of Infectious Diseases, 1976
- SUBTYPING OF HERPES SIMPLEX VIRUSActa Pathologica Microbiologica Scandinavica Section B Microbiology, 1975
- Phosphonoacetic Acid-Resistant Herpes Simplex Virus Infection in Hairless MiceAntimicrobial Agents and Chemotherapy, 1975
- Latent Herpes Simplex Virus in Spinal Ganglia of MiceScience, 1971